In patients from group II, lower ABI was associated with greater duration of the symptoms of PAD (β = −1.31, p < 0.01), age (β = −0.85, p < 0.05), levels of CRP (β = −1.21, p < 0.01) and E-selectin (β = −0.43, p < 0.05); and greater ABI was associated with higher HDL-C (β = 1.23, p < 0.05) and eGFR (β = 0.69, p < 0.05) levels. The gene discussed is CRP; the disease is peripheral arterial disease.