Feng et al. did not find an association between IL-6 promoter polymorphism (-174 G/C) and mortality [18]; they included patients with severe pneumonia-induced sepsis, mean SOFA score of 5 points, microorganism responsible for pneumonia isolated in 38.6%, a rate of septic shock of 34.7%, and a mortality rate of 22.7%. This evidence concerns the gene IL6 and Sepsis.