As previously noted, in a FLT3-ITD AML cell line resistant to FLT3 inhibition, treatment with TP-0903 resensitized the cells to two different FLT3 small molecule inhibitors [81], implicating dual inhibition of FLT3 and AXL as an intriguing therapeutic strategy in AML. Here, FLT3 is linked to acute myeloid leukemia.