In the novel object recognition test, only 3xTg-AD/Fcgr2b KO mice, but not 3xTg-AD mice, discriminated between novel and familiar objects in the second and third trials (Figure 1F), indicating that the recognition memory deficit of 3xTg-AD mice was prevented by Fcgr2b deficiency. The gene discussed is FCGR2B; the disease is Alzheimer disease.