SLC1A2 and ischemia: Most importantly, the neuro-protective effects of ceftriaxone have been shown in middle cerebral artery occlusion-induced focal brain ischaemia, two-vein occlusion-induced ischaemia and transient forebrain ischaemia models35, 36, 37, 38, 39, and they were thought to be related to the upregulation of GLT-1 (refs 35, 36, 39).