One example of a gene which was associated with active states of enhancer probes across all prostate tumors is the CAMKK2 gene, an AR-regulated gene that is an upstream activator of the AMP-dependent protein kinase (AMPK) and is involved in catabolic pathways and physiologically relevant processes such as cell cycle and cytoskeleton reorganization [21]. The gene discussed is CAMKK2; the disease is prostate neoplasm.