MTM1 and metabolic dysfunction-associated steatohepatitis: One study found that a Cnm+/PA+ strain of S. mutans contributed to the aggravation of non-alcoholic steatohepatitis (NASH) in mice but that neither the tested Cnm+/PA− strain nor the tested Cnm−/PA− strain did so7, suggesting that Cnm and PA could be important cell surface proteins for S. mutans-associated aggravation of NASH.