MAPK8 and gastric cancer: To examine whether DACT1α regulated PCP pathway in gastric cancer cells [11, 12, 15], expression of central PCP component Dvl-2 and activation of PCP downstream JNK pathway were determined by western blot in pcDNA3.1 and pcDNA3.1-DACT1α stably transfected BGC823, MGC803 and AGS cells.