IL17A and Autoimmunity: Given that Th17 lymphocyte response is promoted in CFA-induced models of autoimmunity [12], and that more severe EAE in the rat is associated with higher frequency of Th17 cells co-producing IFN-γ and IL-17 in spinal cord (SC) [27,28], multi-cytokine producing Th17 lymphocytes are worthy of special attention in studies of rat susceptibility to EAE.