S100A8 and myocardial infarction: Some of H. pylori strains possess cytotoxin-associated gene-A (CagA), which is one of the major virulence factors of H. pylori and the high prevalence of CagA-positive H. pylori strain has been reported in Japan (94% among Japanese people) [8], and a current study showed a significant association between CagA seropositivity and myocardial infarction [9].