CD8A and thymoma: The positive staining of stathmin in T lymphocytes is supported by previous studies, as stathmin plays a critical role in the activation of T lymphocytes as a regulator of cell polarization and T lymphocyte migration from the vascular compartment across tissue barriers.[57, 58] The use of stathmin to distinguish the different thymoma subtypes is limited due to its staining of lymphocytes as opposed to the tumorous epithelial cells themselves, as CD4 and CD8 are well-established IHC targets for T lymphocytes.[59]