Mouse progenitor 32D cells transfected with the BCR-ABL chimerical cDNA were used as a chronic myelogenous leukemia progenitor model and were also arrested in the G2/M phase after 18 or 24 h of treatment with curcumin 20μM. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.