NCOA3 and breast carcinoma: To investigate whether downregulation of miRNAs increased NCOA3 expression in taxol-resistant breast cancer, we carried out a bioinformatic prediction to search miRNAs targeting the 3′-untranslated region (3′-UTR) of NCOA3. We initially predicted 33 shared target miRNAs of NCOA3 in four online databases (Figure 2a).