In patients with positive lymph node metastasis, 53.6% (59/110) had high expression of ROR1, the percentage decreased to 17.9% in those patients with negative lymph node metastasis, and the P value (P < 0.001) of the difference about the scores in these two group reached the statistical significance (Fig. 2G,H). This evidence concerns the gene ROR1 and metastatic malignant neoplasm in the lymph nodes.