KLK3 and Familial prostate cancer: However, when each model was compared with the NICE guidelines using McNemar’s test, there was no evidence to say any model was better or worse at detecting prostate cancer: PSA alone p value 0.65; age-adjusted PSA p value: 1; BMI-adjusted PSA p value: 0.53; age–BMI-adjusted PSA p value: 1.