In the sensitivity analysis using only men without prostate cancer (n = 9,457), multivariable linear regression showed a 5.51% decrease in PSA per 5 kg/m2 increase in BMI (95% CI 3.62–7.36) and univariable regression showed a 14.25% increase in PSA per 5-year increase in age (95% CI 12.54–15.98). Here, KLK3 is linked to Familial prostate cancer.