Furthermore, in one of the studies it was demonstrated that inflammation, oxidative and nitrosative stress biomarkers such as serum levels of IL-6, TNF-α, IFN-γ, IL-4, IL-10, and IL-17, albumin, ferritin, and plasma levels of CL-LOOH, carbonyl protein, AOPPs, NOx, TRAP, and NcoI TNFβ genotypes might be considered potential predictive biomarkers of high disability in MS (EDSS) and were associated with different aspects of disease progression (higher pyramidal symptoms, sensitive symptoms, and cerebellar symptoms) [83]. This evidence concerns the gene ALB and myeloid sarcoma.