TGFB1 and lung carcinoma: Although miR-29c was reported to directly target the 3′ UTR of Sp1 to repress its expression and regulated type I collagen production under TGF-β1-stimulated kidney fibrosis [15], the relationship between Sp1 and miR-29c in TGF-β-induced EMT during the development of lung cancer was incompletely known.