Interestingly, Tumor Neuroblastoma - SEQC - 498 - RPM - seqcnb1 dataset analysis revealed that a decreased expression of miR-181c in neuroblastoma is linked to a worse overall survival (OS), either considering all neuroblastoma patients (χ2 = 11.34, df = 1, p-value = 7.6e-04, n = 498) or selecting only cases with no MYCN amplification (χ2 = 16.51, df = 1, p-value = 4.8e-05, n = 401) (Figure 4A, 4B). Here, MYCN is linked to neuroblastoma.