CXCR3 and neoplasm: We focused our attention on these markers because CXCR3 signaling is required for T cell infiltration into tumor sites (Mikucki et al., 2015), and the relative intensity of intratumoral T cell infiltration predicts both cancer survival and the response to anti-cancer immunotherapy in humans (Galon et al., 2006, Rooney et al., 2015, Tumeh et al., 2014).