IL6 and Patent ductus arteriosus: Importantly, this observation is consistent with the data from C26- and PDA-bearing mice outlined above (Figure 3A), as well as with previous reports of elevated IL-6 levels in patients with PDA and with other cachexia-associated cancers (Staal-van den Brekel et al., 1995, Fearon et al., 1991, Okada et al., 1998).