This marked sensitivity of the immune C26 tumor microenvironment to corticosterone was also reflected by the correlation between anti-IL-6-induced decreased plasma levels of the hormone and increased mRNA levels of Cxcl9, Cxcl10, and Cxcl11 in food-restricted pre-cachectic C26-bearing mice (Figure S6H). This evidence concerns the gene IL6 and neoplasm.