PRF1 and neoplasm: Since adaptive immune control of tumor growth depends on the intratumoral accumulation and function of T cells (Mikucki et al., 2015, Tumeh et al., 2014), we measured the expression of a panel of eight genes relating to these immune phenomena that were suppressed in tumors from cachectic mice: the CXCR3-dependent chemotaxis of T cells (Cxcl9, Cxcl10, and Cxcl11), the presence of T cells (Cd8a and Cd3e), and their effector functions (Gzmb, Prf1, and Ifng).