The pooled data showed that high GLUT-1 expression was associated with advanced tumor stages (n = 7, OR = 2.99, 95% CI: 2.01–4.46, P < 0.001), higher tumor grade (n = 5, OR = 3.34, 95%CI: 1.12–9.94, P = 0.031), tumor size (n = 5, OR = 3.36, 95%CI: 2.04–5.51, P < 0.001), lymph node metastasis (n = 5, OR = 3.15, 95%CI: 1.89–5.25, P < 0.001), tobacco use (n = 3, OR = 2.18, 95%CI: 1.18–4.01, P = 0.013), and distant metastasis (n = 2, OR = 3.06, 95%CI: 1.19–7.9, P = 0.02). This evidence concerns the gene SLC2A1 and metastatic malignant neoplasm in the lymph nodes.