It is reported that high levels of lat1 are expressed in various tumors including mammary gland tumors, thyroid tumors, neuroendocrine tumors of the lung and hemangiopericytomas compared to normal tissues, and higher expression levels of lat1 in human colon cancers, breast cancers, head and neck cancers, genital cancers and soft-tissue sarcomas from patients were correlated with distant metastasis, suggesting a role for lat1 in the biological behavior of tumors [21,22,23]. This evidence concerns the gene SLC7A5 and head and neck cancer.