TNF and cystic fibrosis: Furthermore TRPA1 specific inhibitors from Hydra Biosciences (HC-030031) and Abbott (A-967079) (Figure 1) [48] inhibited P. aeruginosa induced transcription of IL8, IL1b, IL6 and tumor necrosis factor α (TNFα) in A549 and human cystic fibrosis cell line (CuFi-1).