The average durations of DFS and OS in patients with high level circulating CK7, ELF3, EGFR, and EphB4 mRNAs (tumor PBMCs vs. positive control: >2-fold) were significantly shorter than those of patients with normal or downregulation of the four mRNAs in the PBMCs (Figure 3). The gene discussed is EGFR; the disease is neoplasm.