EMT—characterized by the loss of E-cadherin, the expression of mesenchymal cytoskeleton proteins such as vimentin and fibronectin, and the expression of transcription factors such as Snail, Slug, Twist, and FoxC3—is induced by TGF-β in many cancer cells [41,60,61,62,63]. This evidence concerns the gene TGFB1 and cancer.