Among the genes involved in the development of MetS and/or cardiovascular diseases are the apolipoprotein A5 (APOA5), apolipoprotein C1 (APOC1), BRCA1 associated protein (BRAP), BUD13 homolog (BUD13), cholesteryl ester transfer protein (CETP), lipase A lysosomal acid type (LIPA), lipoprotein lipase (LPL), phospholipase C gamma 1 (PLCG1), and ZPR1 zinc finger (ZPR1) gene. The gene discussed is LIPA; the disease is metabolic syndrome.