XIAP and colorectal carcinoma: XIAP gene, also of the IAP gene family, is also significantly up-regulated in the 100 CRC tissues examined (mean ± SEM: 1.299 ± 0.10 fold expression units) compared to normal counterparts (mean ± SEM: 1.090 ± 0.09 fold expression units) at the mRNA level (p = 0.012), as calculated by the Wilcoxon Signed Ranks test (Tables 1 and 2).