TNFRSF10B and colorectal carcinoma: DR5 showed very significant higher mRNA expression levels in CRC tissues (mean ± SEM: 1.915 ± 0.16 fold expression units) compared to normal counterparts (mean ± SEM: 1.174 ± 0.11 fold expression units) (p < 0.0001), as calculated by the Wilcoxon Signed Ranks test (Tables 1 and 2).