BIRC2 and colorectal carcinoma: cIAP1 gene was found significantly down-regulated in CRC (mean ± SEM: 1.0922 ± 0.08 fold expression units) compared to normal tissue (mean ± SEM: 1.509 ± 0.09 fold expression units) at the mRNA level (p < 0.0001), as calculated by the Wilcoxon Signed Ranks test (Tables 1 and 2).