Patients with Werner syndrome (WS, associated with mutations in the RecQ DNA helicase) manifest with features of systemic chronic inflammation (Davis and Kipling, 2006), including the high serum levels of highly sensitive C-reactive protein (hs-CRP), an acute-phase protein of hepatic origin whose levels are increasing following interleukin-6 (Goto et al., 2012). Here, CRP is linked to Werner syndrome.