The glutamine transporters SLC1A5 (ASCT2) and SLC1A7, which are over-expressed in various human cancers such as colon, liver, colorectal adenocarcinomas, glioblastoma multiforme, and melanoma, have been attractive targets due to their role in cell survival signalling and also being a major source of glutamine delivery [123]. The gene discussed is SLC1A5; the disease is melanoma.