Significant statistical association was found between HO-1(GT)n repeat length polymorphism and CHD risk under an allelic contrast (S vs. L, OR = 0.929, 95%CI = 0.881-0.978, P = 0.005), the recessive genetic model (SS vs. SL+LL, OR = 0.858, 95% CI = 0.780-0.945, P = 0.002), and the co-dominant genetic model (SS vs. LL, OR = 0.843, 95% CI = 0.754-0.942, P = 0.003). The gene discussed is HMOX1; the disease is coronary artery disorder.