The transcripts of the BCC pathway upregulated in our samples were as described by Sturm et al. and included target genes of the SHH pathway like PTCH1 and GLI1, members of the BMP, WNT ligands and WNT ligand receptors families and of the LEF1 and TCF7L1 beta-catenin transcription complex. This evidence concerns the gene SHH and skin basal cell carcinoma.