Yin et al. showed that phosphatase 2A catalytic subunit (PP2Ac), which was a target for cisplatin, suppressed the accumulation of LC3-II and restored p62, knocking down of PP2A promoted autophagy in cisplatin-resistant ovarian cancer cells, suggesting protective autophagy inhibited by PP2Ac is a part of the mechanism to how certain ovarian cancers are resistant to cisplatin [53]. This evidence concerns the gene PTPA and ovarian carcinoma.