Interestingly, AML cell lines were more sensitive to AC inhibition with LCL204 (EC50 5.1 μM ± 0.2 SEM, n=7) than normal BM CD34+ cells (EC50 6.0 μM, n=1) and normal mobilized PBMC CD34+ cells (EC50 7.2 μM ± 0.4 SEM, n=4). This evidence concerns the gene CD34 and acute myeloid leukemia.