From meta-analysis results, it found that the over-expressed H19 was associated with poor histological grade (OR=2.31, 95% CI: 1.12-4.75, p=0.02), positive lymph node metastasis (OR=2.29, 95% CI: 1.21-4.34, p=0.01), and advanced TNM stage (OR=4.83, 95% CI: 3.16-7.39, p<0.001). This evidence concerns the gene H19 and metastatic malignant neoplasm in the lymph nodes.