Intriguingly, addition of NCOR1, NCOR2, and ZBTB16 to AR and FOXA1 empowers an association with PC recurrence (Figure 10C); in fact AR plus NCOR1, NCOR2, and ZBTB16 is almost sufficient to predict a reduction in DFS (Supplementary Figure S12). The gene discussed is AR; the disease is pachyonychia congenita.