NTRK2 and Cognitive impairment: We found that decreased BDNF-TrkB signaling in the PFC and CA1 of the hippocampus may play a role in the cognitive deficits observed in offspring from poly(I:C)-treated mice and that supplementation of 7,8-DHF at 4–8 weeks of age (similar to juvenile and adolescent stages in human) in poly(I:C) offspring could treat or prevent cognitive deficits and PPI deficits at adulthood after MIA.