PEDS1 and neoplasm: To elucidate the molecular mechanisms of the growth and migration inhibition effects of KuA on human GBM cells in vitro and in vivo, the expressions of 5-Lipoxygenase, apoptotic proteins, CCAAT/enhancer binding protein β (C/EBPβ) and EMT associated proteins in KuA treated GBM cells and tumor tissues were analyzed with Western blotting.