To explore the deregulated gene expression characteristics of MEF2D-rearranged ALL, we perform the gene set enrichment analysis (GSEA) and pathway analysis and demonstrated that MEF2D-rearranged cases exhibited a gene expression profile of a later maturational stage than other subtypes of ALL (Supplementary Data 8 and 9). The gene discussed is MEF2D; the disease is acute lymphoblastic leukemia.