CCR3 and early-onset autosomal dominant Alzheimer disease: Expression of CCR3 is elevated in the setting of human immunodeficiency virus infection (van der Meer et al., 2000; Van Der Meer et al., 2001), and elevated expression of CCR3 is observed in reactive microglia and astrocytes around the amyloid deposits in Alzheimer’s disease (Xia et al., 1998).