To examine the levels of cytokines and VEGF produced in tumor tissues treated with RdB (3 × 109 VP), RdB/shVEGF (3 × 109 VP), RdB/IL12 (6 × 108 VP), or RdB/IL12/shVEGF (6 × 108 VP), tumor tissues were harvested 12 days after initial viral injection. Here, VEGFA is linked to neoplasm.