Therefore, in contrast to ALS studies including ours, over‐activation of MAM function seems to be involved in neurodegeneration in AD, while parkin, DJ‐1, and α‐synuclein, the gene products of inherited PD, are required for neuroprotective function of the MAM and interaction with ER and mitochondria (Paillusson et al, 2016). The gene discussed is PARK7; the disease is amyotrophic lateral sclerosis.