Recessive mutations in SIGMAR1 have recently been identified as a causative gene for ALS with or without frontotemporal lobar degeneration (FTLD) (Luty et al, 2010; Ullah et al, 2015), juvenile ALS (ALS16) (Al‐Saif et al, 2011), and distal hereditary motor neuropathy (dHMN) (Li et al, 2015; Gregianin et al, 2016). The gene discussed is SIGMAR1; the disease is amyotrophic lateral sclerosis.