SIX4 mRNA expression: NSCLC/normal: Begg’s test p = 0.734, Egger’s test p = 0.656; ADC/normal: Begg’s test p = 1.000, Egger’s test p = 0.702; III~IV/I~II: Begg’s test p = 0.086, Egger’s test p = 0.070; ADC-III~IV/ADC-I~II: Begg’s test p = 0.308, Egger’s test p = 0.165; ADC/SQC: Begg’s test p = 0.548, Egger’s test p = 0.871; OS of NSCLC: Begg’s test p = 0.230, Egger’s test p = 0.062; RFS of NSCLC: Begg’s test p = 0.734, Egger’s test p = 0.871; RFS of ADC: Begg’s test p = 0.734, Egger’s test p = 0.381. The gene discussed is SIX4; the disease is non-small cell lung carcinoma.