HMOX1 and coronary artery disorder: Additionally, significant correlations were found in the non-CAD group, respectively, between HO-1 and HIF-1 (rs = 0.25, P < 0.05), p38MAPK and HIF-1 (rs = 0.20, P < 0.05), p38MAPK and HO-1 (rs = 0.12, P < 0.05) (Fig. 1).