SFRP2 and breast carcinoma: Besides our findings, recent literature has also reported enhanced expression of sFRP2 in angiosarcoma and breast cancer, and analysis of multiple publicly available datasets (cBioPortal for Cancer Genomics, http://www.cbioportal.org) revealed relatively elevated levels of sFRP2 in sarcomas (Additional file 1: Figure S1a; red box highlighting sarcomas).