Taken together, although it has been reported that the effects of FTO variants on obesity risk may be reduced in older individuals like our participants in this study [41,42], an insufficient study power because of the smaller sample size in this study may be a principal cause of the discrepancy between this study and several previously reported studies examining European populations [1,2,5,6,39,40,42–45] and the marginal association of FTO SNPs with T2D after adjusting for the current BMI (Table 5). This evidence concerns the gene FTO and obesity due to melanocortin 4 receptor deficiency.