In addition to hematopoietic malignancies, SALL4 is also found to be upregulated in solid tumours including liver cancer,13, 14 colon cancer,15, 16 breast cancer,17, 18 endometrial cancer,19, 20 lung cancer21, 22 and glioma.23 The recent studies also suggest an oncogenic role of SALL4 in solid tumours. The gene discussed is SALL4; the disease is glioma.