Despite of the contradictory facts that merely STMN2 is a novel target of β-catenin/TCF signaling in hepatoma cells52, we found several potential TCF-bindings sites within the stmn4 promoter (data not shown) also implies that Wnts directly regulate stmn4 at the transcriptional level. This evidence concerns the gene STMN4 and hepatocellular carcinoma.