Similarly, previous studies have confirmed that high IL-17 expression is significantly associated with high MVD by CD31 or CD34 staining in many types of tumours, such as human ovarian cancer24, 25, hepatocellular carcinoma26, multiple myeloma27, colorectal carcinoma28, cholangiocarcinoma tumours29 and NSCLC7. This evidence concerns the gene PECAM1 and neoplasm.