To further test whether NKG2D activates or inhibits production of IFNγ, the absolute number of IFNγ+ NK cells was analyzed in both the anti-NKG2D antibody neutralization and IgG1 control groups, two weeks after inoculation of Notch1-T-ALL leukemia cells. This evidence concerns the gene KLRK1 and acute lymphoblastic leukemia.