NPHS1 and focal segmental glomerulosclerosis: Similar to other human gene expression studies of FSGS [38–40], the expression of podocyte-specific genes including NPHS1, NPHS2, and WT1 were downregulated in the SIOD kidney, and most of the KEGG pathways that were enriched in our list of upregulated genes were also enriched in the prior studies, including the Wnt signaling pathway [38].