CCR7 and metastatic malignant neoplasm in the lymph nodes: Consistent with miR-199a-5p, CCR7 upregulation was also correlated with TNM stage (P < 0.011), Histological grade (P = 0.001), Tumor invasion depth (T) (P < 0.001) and Lymph node metastasis (N) (P < 0.001) (Table 2).